Bacteriol . and Andrew K . Benson Mehmet Sevket Cetin , Chaomei Zhang , Robert W . Hutkins monocytogenes Listeria , in B σ Sigma Factor , Solute Transporters by the General Stress Regulation
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Regulation of transcription of compatible solute transporters by the general stress sigma factor, sigmaB, in Listeria monocytogenes.
Listeria monocytogenes is well known for its durable physiological characteristics, which allow the organism to grow at low temperature and pH and high osmolarity. Growth under high osmolarity depends on the accumulation of compatible solutes, among which glycine betaine and carnitine are the preferred solutes for this organism. Three different transport systems, Gbu, BetL, and OpuC, have been ...
متن کاملIdentification of the Gene Encoding the Alternative Sigma Factor s from Listeria monocytogenes and Its Role in Osmotolerance†
Listeria monocytogenes is well known for its robust physiology, which permits growth at low temperatures under conditions of high osmolarity and low pH. Although studies have provided insight into the mechanisms used by L. monocytogenes to allay the physiological consequences of these adverse environments, little is known about how these responses are coordinated. In the studies presented here,...
متن کاملIdentification of the gene encoding the alternative sigma factor sigmaB from Listeria monocytogenes and its role in osmotolerance.
Listeria monocytogenes is well known for its robust physiology, which permits growth at low temperatures under conditions of high osmolarity and low pH. Although studies have provided insight into the mechanisms used by L. monocytogenes to allay the physiological consequences of these adverse environments, little is known about how these responses are coordinated. In the studies presented here,...
متن کاملThe Listeria monocytogenes σB Regulon and Its Virulence-Associated Functions Are Inhibited by a Small Molecule
UNLABELLED The stress-responsive alternative sigma factor σ(B) is conserved across diverse Gram-positive bacterial genera. In Listeria monocytogenes, σ(B) regulates transcription of >150 genes, including genes contributing to virulence and to bacterial survival under host-associated stress conditions, such as those encountered in the human gastrointestinal lumen. An inhibitor of L. monocytogene...
متن کاملStructural and functional characterisation of partner-switching regulating the environmental stress response in B. subtilis
The general stress response of Bacillus subtilis and close relatives provides the cell with protection from a variety of stresses. The upstream component of the environmental stress signal transduction cascade is activated by the RsbT kinase that switches binding partner from a 25S macromolecular complex, the stressosome, to the RsbU phosphatase. Once the RsbU phosphatase is activated by intera...
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تاریخ انتشار 2003